1make (someone) feel isolated or estranged:an urban environment which would alienate its inhabitants (as adjective alienated)an alienated, angst-ridden twenty-two-year-old
make (someone) become unsympathetic or hostile:the association does not wish to alienate its members
2 Law transfer ownership of (property rights) to another person or group:they defended the Masai against attempts to alienate their land
alienate someone's affections
US Law induce someone to transfer their affection from a person (such as a spouse) with legal rights or claims on them:he sued him for alienating his wife’s affections
